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  1. Diabetic peripheral neuropathy (DPN) is a chronic microvascular complication of diabetes. The purpose of this study is to find the underlying mechanism for the effects of acupuncture in DPN rats. Rats were ren...

    Authors: He-yong Tang, Fan-jing Wang, Jun-long Ma, Hao Wang, Guo-ming Shen and Ai-juan Jiang

    Citation: The Journal of Physiological Sciences 2020 70:45

    Content type: Original Paper

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  2. Glucose uptake and adenosine triphosphate (ATP) generation are important for the survival and growth of endothelial cells. An increase of glucose uptake under hypoxia was previously shown to be associated with...

    Authors: Abdullah Al Mamun, Hisaki Hayashi, Aya Yamamura, Md Junayed Nayeem and Motohiko Sato

    Citation: The Journal of Physiological Sciences 2020 70:44

    Content type: Original Paper

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  3. The relationship between long-term intensive training and brain plasticity in gymnasts has recently been reported. However, the relationship between abilities in different gymnastic events and brain structural...

    Authors: Makoto Fukuo, Koji Kamagata, Mana Kuramochi, Christina Andica, Hiroyuki Tomita, Hidefumi Waki, Hidenori Sugano, Yuichi Tange, Takumi Mitsuhashi, Wataru Uchida, Yuki Takenaka, Akifumi Hagiwara, Mutsumi Harada, Masami Goto, Masaaki Hori, Shigeki Aoki…

    Citation: The Journal of Physiological Sciences 2020 70:43

    Content type: Original Paper

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  4. Metabolic disorders can induce psychiatric comorbidities. Both brain and neuronal composition imbalances reportedly induce an anxiety-like phenotype. We hypothesized that alterations of localized brain areas a...

    Authors: Ryosuke Ochi, Naoto Fujita, Natsuki Goto, Son Tien Nguyen, Duc Trung Le, Kojiro Matsushita, Taketoshi Ono, Hisao Nishijo and Susumu Urakawa

    Citation: The Journal of Physiological Sciences 2020 70:42

    Content type: Original Paper

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  5. The present study aimed to clarify if stroking stimulation of the skin produces positive emotion in rats. 50-kHz ultrasonic vocalizations (USVs) were recorded as an index of the positive emotion. Stroking stim...

    Authors: Rie Shimoju, Hideshi Shibata, Miyo Hori and Mieko Kurosawa

    Citation: The Journal of Physiological Sciences 2020 70:41

    Content type: Short Communication

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  6. Skeletal muscle is one of the most abundant and highly plastic tissues. The ubiquitin–proteasome system (UPS) is recognised as a major intracellular protein degradation system, and its function is important fo...

    Authors: Yasuo Kitajima, Kiyoshi Yoshioka and Naoki Suzuki

    Citation: The Journal of Physiological Sciences 2020 70:40

    Content type: Review

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  7. Signal regulators during early cardiogenetic differentiation for the cellular automaticity are largely unknown. Our investigations were designed to clarify the role of transcription factors and their modulator...

    Authors: Mingqi Zheng, Lin Kang, Tomoko Uchino, Gang Liu, Yan Wang and Katsushige Ono

    Citation: The Journal of Physiological Sciences 2020 70:39

    Content type: Original Paper

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  8. Electrical disparity can induce inefficient cardiac performance, representing an uncoordinated wall motion at an earlier activated ventricular wall: an early shortening followed by a systolic rebound stretch. ...

    Authors: Yohsuke Hayama, Shuji Shimizu, Toru Kawada, Jun Negishi, Heima Sakaguchi, Aya Miyazaki, Hideo Ohuchi, Osamu Yamada, Kenichi Kurosaki and Masaru Sugimachi

    Citation: The Journal of Physiological Sciences 2020 70:38

    Content type: Original Paper

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  9. Although anatomical studies have indicated pudendal motoneurons to give off recurrent collaterals, they are not considered to make synapses onto interneurons, such as Renshaw cells, and rather terminate their ...

    Authors: Ken Muramatsu, Masatoshi Niwa and Sei-Ichi Sasaki

    Citation: The Journal of Physiological Sciences 2020 70:37

    Content type: Short Communication

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  10. ST elevation on an electrocardiogram is a hallmark of acute transmural ischemia. However, the underlying mechanism remains unclear. We hypothesized that high ischemic sensitivities of epicardial adenosine trip...

    Authors: Jun-ichi Okada, Katsuhiko Fujiu, Kazunori Yoneda, Takashi Iwamura, Takumi Washio, Issei Komuro, Toshiaki Hisada and Seiryo Sugiura

    Citation: The Journal of Physiological Sciences 2020 70:36

    Content type: Original Paper

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  11. Cisplatin is one of the most potent anti-cancer drugs, though several side effects can induce stress responses such as activation of the hypothalamic–pituitary adrenal (HPA) axis. Arginine vasopressin (AVP) an...

    Authors: Yasuki Akiyama, Mitsuhiro Yoshimura, Hiromichi Ueno, Kenya Sanada, Kentaro Tanaka, Satomi Sonoda, Haruki Nishimura, Kazuaki Nishimura, Yasuhito Motojima, Reiko Saito, Takashi Maruyama, Keiji Hirata, Yasuhito Uezono and Yoichi Ueta

    Citation: The Journal of Physiological Sciences 2020 70:35

    Content type: Original Paper

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  12. Maternal–fetal calcium (Ca2+) transport in the placenta plays a critical role in maintaining fetal bone mineralization. Mutations in the gene encoding the transient receptor potential cation channel, subfamily V,...

    Authors: Yoshiro Suzuki, Hirotake Sawada, Tomoko Tokumasu, Shigeru Suzuki, Shinsuke Ninomiya, Masaru Shirai, Tokuo Mukai, Claire T. Saito, Gen Nishimura and Makoto Tominaga

    Citation: The Journal of Physiological Sciences 2020 70:33

    Content type: Original Paper

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  13. Primary acute sympathetic activation (PASA) can increase arterial pressure (AP). Under this situation, the kidneys may receive mutually opposing influences from sympathetic activation: a direct anti-diuretic e...

    Authors: Toru Kawada, Yohsuke Hayama, Takuya Nishikawa, Satoru Suehara, Satoshi Sawada, Tetsuo Tanaka, Minako Uenohara and Masaru Sugimachi

    Citation: The Journal of Physiological Sciences 2020 70:32

    Content type: Original Paper

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  14. Thirty sedentary overweight women were randomly assigned to three groups (n = 10), including HIIT + green tea, HIIT + placebo and green tea. The training program included 3 sessions/week HIIT while the supplement...

    Authors: Elham Ghasemi, Mohammad Esmaeil Afzalpour and Shila Nayebifar

    Citation: The Journal of Physiological Sciences 2020 70:31

    Content type: Original Paper

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  15. This study examined the effect of olfactory nerve stimulation on regional cerebral blood flow and assessed the effect of intravenous nicotine administration on this response in anesthetized rats. Regional cere...

    Authors: Sae Uchida and Fusako Kagitani

    Citation: The Journal of Physiological Sciences 2020 70:30

    Content type: Original Paper

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  16. Tolfenamic acid, a nonsteroidal anti-inflammatory drug, alleviated learning and memory deficits and decreased the expression of specificity protein 1 (SP1)-mediated cyclin-dependent kinase-5 (CDK5), a major pr...

    Authors: Huiming Zhang, Xiaojuan Wang, Pu Xu, Xuefei Ji, Tianyan Chi, Peng Liu and Libo Zou

    Citation: The Journal of Physiological Sciences 2020 70:29

    Content type: Original Paper

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  17. The efficacy of insulin-like growth factor 1 (IGF-1) in the treatment of peripheral facial nerve palsy was investigated using an animal model. The facial nerve within the temporal bone was exposed and compress...

    Authors: Motoyasu Sugiyama, Tsukasa Ito, Takatoshi Furukawa, Atsushi Hirayama and Seiji Kakehata

    Citation: The Journal of Physiological Sciences 2020 70:28

    Content type: Original Paper

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  18. Neuropsin is a brain-expressed extracellular matrix serine protease that governs synaptic plasticity through activity-induced proteolytic cleavage of synaptic proteins. Its substrates comprise several molecule...

    Authors: Lina Bukowski, Ana M. F. Chernomorchenko, Anna Starnawska, Ole Mors, Nicklas H. Staunstrup, Anders D. Børglum and Per Qvist

    Citation: The Journal of Physiological Sciences 2020 70:26

    Content type: Review

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  19. We investigated that the effects of hypercapnia-induced elevations in cerebral perfusion during a heat stress on global cerebrovascular responses to an orthostatic challenge. Seven volunteers completed a progr...

    Authors: Manabu Shibasaki, Kohei Sato, Ai Hirasawa, Tomoko Sadamoto, Craig G. Crandall and Shigehiko Ogoh

    Citation: The Journal of Physiological Sciences 2020 70:25

    Content type: Original Paper

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  20. To quantify the dynamics of blood flow in brachial artery (BF-BA) in response to sinusoidal work rate (WR) leg cycling exercises of 2-, 4-, and 6-min periods and to examine their relationship with the forearm ...

    Authors: Kohei Miura, Hideaki Kashima, Anna Oue, Ayaka Kondo, Sachiko Watanabe, Masako Y. Endo and Yoshiyuki Fukuba

    Citation: The Journal of Physiological Sciences 2020 70:23

    Content type: Original Paper

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  21. The skin temperature (Tm) of the orofacial area influences orofacial functions and is related to the blood flow (BF). Marked increases in BF mediated by parasympathetic vasodilation may be important for orofacial...

    Authors: Hanako Ohke, Toshiya Sato, Kohei Mito, Makoto Terumitsu and Hisayoshi Ishii

    Citation: The Journal of Physiological Sciences 2020 70:22

    Content type: Original Paper

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  22. Blood pressure response to head-up tilt (HUT) in 7 healthy subjects and 9 patients before and after coronary artery bypass grafting (CABG) was measured during supine and 15-min 60° HUT. Stroke volume (SV) and ...

    Authors: Shinnosuke Hori, Yoshi-ichiro Kamijo, Mitsuru Yuzaki, Tetsuya Kawabe, Kohei Minami, Yasunori Umemoto, Mao Yokoyama, Hiroyasu Uenishi, Yoshiharu Nishimura, Ken Kouda, Yukio Mikami and Fumihiro Tajima

    Citation: The Journal of Physiological Sciences 2020 70:21

    Content type: Original Paper

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  23. The homeobox-containing gene Csx/Nkx2.5 codes several cardiac transcription factors and plays a critical role in early cardiogenesis. We investigated the effect of Csx/Nkx2.5 on the expression of cardiac ion c...

    Authors: Tomoko Uchino, Ming-Qi Zheng, Yan Wang and Katsushige Ono

    Citation: The Journal of Physiological Sciences 2020 70:20

    Content type: Original Paper

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  24. High-fat diet (HFD) can induce deficits in neural function, oxidative stress, and decrease hippocampal neurogenesis. Hypericum (H.) scabrum extract (Ext) contains compounds that could treat neurological disorders...

    Authors: Ghazaleh Omidi, Arezoo Rezvani-Kamran, Ahmad Ganji, Somayeh Komaki, Farshid Etaee, Masoumeh Asadbegi and Alireza Komaki

    Citation: The Journal of Physiological Sciences 2020 70:19

    Content type: Original Paper

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  25. Class II phosphatidylinositol 3-kinases (PI3K), PI3K-C2α and PI3K-C2β, are involved in cellular processes including endocytosis, cilia formation and autophagy. However, the role of PI3K-C2α and PI3K-C2β at the...

    Authors: Shahidul Islam, Kazuaki Yoshioka, Sho Aki, Kazuhiro Ishimaru, Hiroki Yamada, Noriko Takuwa and Yoh Takuwa

    Citation: The Journal of Physiological Sciences 2020 70:18

    Content type: Original Paper

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  26. The peripheral vestibular organs are sensors for linear acceleration (gravity and head tilt) and rotation. Further, they regulate various body functions, including body stability, ocular movement, autonomic ne...

    Authors: Hironobu Morita, Hiroshi Kaji, Yoichi Ueta and Chikara Abe

    Citation: The Journal of Physiological Sciences 2020 70:17

    Content type: Review

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  27. Respiratory disturbances present in Parkinson’s disease (PD) are not well understood. Thus, studies in animal models aimed to link brain dopamine (DA) deficits with respiratory impairment are needed. Adult Wis...

    Authors: Kryspin Andrzejewski, Monika Jampolska, Małgorzata Zaremba, Ilona Joniec-Maciejak, Paweł M. Boguszewski and Katarzyna Kaczyńska

    Citation: The Journal of Physiological Sciences 2020 70:16

    Content type: Original Paper

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  28. The purpose of the present study was to assess the effect of different water immersion temperatures on handgrip performance and haemodynamic changes in the forearm flexors of males and females. Twenty-nine roc...

    Authors: Jiří Baláš, Jan Kodejška, Dominika Krupková and David Giles

    Citation: The Journal of Physiological Sciences 2020 70:13

    Content type: Original Paper

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  29. Experiments on animal hearts (rat, rabbit, guinea pig, etc.) have demonstrated that mechano-calcium feedback (MCF) and mechano-electric feedback (MEF) are very important for myocardial self-regulation because ...

    Authors: Nathalie A. Balakina-Vikulova, Alexander Panfilov, Olga Solovyova and Leonid B. Katsnelson

    Citation: The Journal of Physiological Sciences 2020 70:12

    Content type: Original Paper

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  30. Pathophysiological functions of chloride intracellular channel protein 3 (CLIC3) in human gastric cancer have been unclear. In the tissue microarray analysis using 107 gastric cancer specimens, CLIC3 expressio...

    Authors: Shunsuke Kawai, Takuto Fujii, Takahiro Shimizu, Kenta Sukegawa, Isaya Hashimoto, Tomoyuki Okumura, Takuya Nagata, Hideki Sakai and Tsutomu Fujii

    Citation: The Journal of Physiological Sciences 2020 70:15

    Content type: Original Paper

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  31. Oral administration of donepezil, a centrally acting acetylcholinesterase inhibitor, improves the survival of rats with chronic heart failure (CHF). The mechanisms of cardioprotective effects of donepezil, how...

    Authors: Meihua Li, Can Zheng, Toru Kawada, Masashi Inagaki, Kazunori Uemura and Masaru Sugimachi

    Citation: The Journal of Physiological Sciences 2020 70:11

    Content type: Original Paper

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  32. Exercise has been reported to induce autophagy. We hypothesized that exercise preconditioning (EP)-related autophagy in cardiomyocytes could be attributed to intermittent ischemia–hypoxia, allowing the heart t...

    Authors: Jian-Qi Yuan, Yang Yuan, Shan-Shan Pan and Ke Cai

    Citation: The Journal of Physiological Sciences 2020 70:10

    Content type: Original Paper

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  33. Pulmonary vein (PV) cardiomyocytes have the potential to generate spontaneous activity, in contrast to working myocytes of atria. Different electrophysiological properties underlie the potential automaticity o...

    Authors: Daichi Takagi, Yosuke Okamoto, Takayoshi Ohba, Hiroshi Yamamoto and Kyoichi Ono

    Citation: The Journal of Physiological Sciences 2020 70:6

    Content type: Original Paper

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  34. While our recent studies have suggested that effective acupoints display neurogenic inflammation and can be identified as neurogenic spots (Neuro-Sps), the optimal stimulation conditions and the underlying mec...

    Authors: Joo Hyun Shin, Yu Fan, Do-Hee Kim, Han Byeol Jang, Suchan Chang, Yeonhee Ryu, Jong Han Bae, Sanghag Lee, Bong Hyo Lee, Scott C. Steffensen, Chae Ha Yang and Hee Young Kim

    Citation: The Journal of Physiological Sciences 2020 70:14

    Content type: Original Paper

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  35. We have previously reported that the negative inotropic effects of hyperthermia (42 °C) on left ventricular (LV) mechanoenergetics using the excised, cross-circulated rat heart model. Here, we investigated the...

    Authors: Koji Obata, Hironobu Morita and Miyako Takaki

    Citation: The Journal of Physiological Sciences 2020 70:4

    Content type: Original Paper

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  36. The present study aimed to investigate whether endurance exercise-induced changes in blood plasma composition may lead to adaptations in erythrocytes, skeletal muscle and liver. Forty sedentary rats were rando...

    Authors: Georgios Goutianos, Nikos V. Margaritelis, Theodora Sparopoulou, Aristidis S. Veskoukis, Ioannis S. Vrabas, Vassilis Paschalis, Michalis G. Nikolaidis and Antonios Kyparos

    Citation: The Journal of Physiological Sciences 2020 70:3

    Content type: Original Paper

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  37. Fragrance inhalation of essential oils is widely used in aromatherapy, and it is known to affect blood pressure (BP) and heart rate (HR) via autonomic control of circulation. In this study, we aimed to test th...

    Authors: Eriko Kawai, Ryosuke Takeda, Akemi Ota, Emiko Morita, Daiki Imai, Yuta Suzuki, Hisayo Yokoyama, Shin-ya Ueda, Hidehiro Nakahara, Tadayoshi Miyamoto and Kazunobu Okazaki

    Citation: The Journal of Physiological Sciences 2020 70:2

    Content type: Original Paper

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  38. We hypothesized that cerebral blood flow (CBF) regulation in the posterior circulation differs from that of the anterior circulation during a cold pressor test (CPT) and is accompanied by elevations in arteria...

    Authors: Takuro Washio, Hironori Watanabe and Shigehiko Ogoh

    Citation: The Journal of Physiological Sciences 2020 70:1

    Content type: Original Paper

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  39. This brief review summarizes the current knowledge on sex differences in baroreflex function, with a major focus on studies in humans. It has been demonstrated that healthy women have blunted cardiovagal baror...

    Authors: Qi Fu and Shigehiko Ogoh

    Citation: The Journal of Physiological Sciences 2019 69:727

    Content type: Review

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  40. The cardiovascular effects of the autonomic nervous system (ANS) are modulated by inputs from peripheral sensors and other brain regions. However, it currently remains unknown whether the manual acupuncture (M...

    Authors: Hidehiro Nakahara, Toru Kawada, Shin-ya Ueda, Eriko Kawai, Hiromi Yamamoto, Masaru Sugimachi and Tadayoshi Miyamoto

    Citation: The Journal of Physiological Sciences 2019 69:728

    Content type: Original Paper

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  41. We aimed to identify the neurotransmitters and brain regions involved in exercise efficiency in mice during continuous complicated exercises. Male C57BL/6J mice practiced treadmill running with intermittent ob...

    Authors: Tetsuya Shiuchi, Takuya Masuda, Noriyuki Shimizu, Sachiko Chikahisa and Hiroyoshi Séi

    Citation: The Journal of Physiological Sciences 2019 69:722

    Content type: Original Paper

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  42. Expiratory (E) neurons in the caudal nucleus retroambigualis extend descending spinal axons to the lumbar and sacral spinal cord. Discharge rates of single E neurons were recorded to examine differences in act...

    Authors: Sei-Ichi Sasaki, Ken Muramatsu and Masatoshi Niwa

    Citation: The Journal of Physiological Sciences 2019 69:715

    Content type: Original Paper

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  43. Diarrhea is a gastrointestinal symptom associated with systemic anaphylaxis and could be induced by increased colonic motility. We determined colonic motility and expulsion by measuring the intracolonic pressu...

    Authors: Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Yuhichi Kuda, Wei Yang and Yasutaka Kurata

    Citation: The Journal of Physiological Sciences 2019 69:710

    Content type: Original Paper

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  44. This study determined whether blockade of 5-hydroxytryptamine 2A (5-HT2A) receptors attenuated hyperthermia and tachycardia responses to psychological stress in mice. For this purpose, male mice (C57BL/6N) wer...

    Authors: Vanshika Sinh and Youichirou Ootsuka

    Citation: The Journal of Physiological Sciences 2019 69:703

    Content type: Short Communication

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2019 Journal Metrics

  • Speed
    44.8 days from submission to first decision
    (reviewed manuscripts)
    34.7 days from submission to first decision
     (all manuscripts)
    117.1 days from acceptance to publication

    Citation Impact
    2.955 - 2-year Impact Factor
    2.536 - 5-year Impact Factor

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