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Table 2 Kinetic parameters of the relaxation processes in the presence or absence of CC-D

From: Effects of cytochalasin D on relaxation process of skinned taenia cecum and carotid artery from guinea pig

 

Taenia cecum

Carotid artery

 

control

1 μM

10 μM

control

1 μM

10 μM

τfast-detach(sec)

35.3 ± 3.8

41.1 ± 4.4

42.7 ± 2.6

139.3 ± 11.9

156.9 ± 23.9

155.4 ± 10.9

τslow-attach(sec)

21.7 ± 5.1

27.4 ± 4.4

23.3 ± 4.4

4.0 ± 1.2

24.3 ± 9.7

5.4 ± 5.3

τslow-detach(sec)

1,920.6 ± 367.1

1,560.3 ± 369.6

796.9 ± 109.5*

1,056.4 ± 238.3

891.6 ± 166.4

435.2 ± 72.8*

A

0.38 ± 0.07

0.29 ± .05

0.23 ± 0.06*

0.67 ± 0.06

0.69 ± 0.08

0.24 ± 0.16*

  1. Kinetic parameters of the relaxation processes of the skinned taenia cecum and carotid artery of the guinea pig in Relaxing solution (with CTP) in the presence or absence of CC-D. Parameters of τfast-detach, τslow-attach, τslow-detach and A represent the rate constants of fast detaching, slowly attaching and slow detaching cross-bridge, and the rate of re-attachment of detached crossbridge, respectively. Values represent mean ± S.E.M. (taenia cecum n = 8, carotid artery n = 8) *P < 0.05
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The Journal of Physiological Sciences

ISSN: 1880-6562

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