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Table 4 Hemodynamics of left ventricle and myocardial mechanics after strength training program

From: Strength training improves heart function, collagen and strength in rats with heart failure

Parameters

C

MI

MIT

F

p

Hemodynamics

 HR (bpm)

357 ± 33

344 ± 26

333 ± 21

1.76

0.1914

 LVSP (mmHg)

117 ± 7

105 ± 7*

113 ± 6†

8.47

0.0015

 LVEDP (mmHg)

3 ± 1

17 ± 7*

10 ± 5*†

17.62

 < 0.0001

  +dP/dtmax (mmHg/s)

8,863 ± 763

4,716 ± 1,211*

7,355 ± 1,408*†

33.35

 < 0.0001

 -dP/dtmax (mmHg/s)

6,090 ± 551

3,602 ± 715*

4,959 ± 754*†

33.97

 < 0.0001

Myocardial mechanics

 DT (g/mm2)

6.24 ± 0.27

2.36 ± 0.28*

3.81 ± 0.24*†

54.12

 < 0.0001

 RT (g/mm2)

1.04 ± 0.09

1.00 ± 0.06

1.07 ± 0.08

0.13

0.8716

  +dT/dtmax (g/mm2/s)

61.56 ± 4.75

18.83 ± 2.85*

35.01 ± 1.64*†

39.46

 < 0.0001

 -dT/dtmax (g/mm2/s)

45.47 ± 3.22

11.32 ± 1.66*

21.94 ± 1.33*†

57.97

 < 0.0001

 TPT (ms)

174.00 ± 7.02

259.90 ± 9.74*

233.30 ± 10.37*

23.89

 < 0.0001

 TR50% (ms)

139.77 ± 7.72

217.20 ± 14.36*

204.40 ± 12.84*

13.02

0.0001

  1. Values expressed as mean ± SEM of the control (C, n = 10), infarcted (MI, n = 10) and infarcted and trained (MIT, n = 9) groups.
  2. HR: heart rate, LVSP: left ventricular systolic pressure, LVEDP: left ventricular end-diastolic pressure, +dP/dtmax: maximum rate of positive variation in LV pressure, -dP/dtmax: maximum rate of negative variation in developed pressure, DT: developed tension, RT: rest tension, +dT/dt: maximum rate of positive variation of tension, -dT/dtmax: maximum rate of negative variation of tension, TPT: time to peak of tension. TR50%: time for RT to decay by 50%
  3. *p < 0.05 vs. C. †p < 0.05 vs. MI, by 1-way ANOVA plus Tukey’s post hoc