Physiology of the volume-sensitive/regulatory anion channel VSOR/VRAC. Part 1: from its discovery and phenotype characterization to the molecular entity identification

Table 3 Pharmacological properties of VSOR/VRAC

Broad specificity	Sensitivity to conventional type of Cl⁻ channel blockers with two aromatic rings connected with a chain of several atoms
	Sensitivity to etacrynic acid derivatives with a 2,3-dichlorophenoxyl fragment
Open-channel blocking	Depolarization-induced blocking by the pore-plugging action of anionic chemicals from the extracellular side

ISSN: 1880-6562