Fig. 8
From: Neurochemical mechanism of muscular pain: Insight from the study on delayed onset muscle soreness
Modified from Murase et al. [38]
GDNF-induced mechanical sensitization occurs in muscle Aδ-fibers. a: Response threshold (left) and response magnitude (right) to a ramp mechanical stimulation from 0 to 196 mN in 10 s in Aδ-fibers (n = 14 each). Significant changes were observed after 60 (threshold) and 30 min (magnitude). b: Those of C-fibers (n = 30 each). No changes were observed in either the mechanical threshold or response magnitude.