Table 2 Cellular urate flow based on the localization of the expressed influx (row) and efflux (column) transporters
From: Identification of three distinct cell populations for urate excretion in human kidneys
| Â | Localization of Efflux transporters | ||||
|---|---|---|---|---|---|
None (AE(−), BE(−)) | Apical (AE( +), BE(−)) | Apical + Basolateral (AE(+), BE(+)) | Basolateral (AE(−), BE(+)) | ||
Localization of Influx Transporters (Cell population) | Apical (AIP) | Unfunctional | Unfunctional | Reabsorption | Reabsorption |
Apical + Basolateral (DIP) | ? | Secretion | Bi-direction | Reabsorption | |
Basolateral (BIP) | Unfunctional | Secretion | Secretion | Unfunctional | |
None (DIN) | Unfunctional | Unfunctional | Unfunctional | Unfunctional | |