Fig. 2

Persistent synaptic plasticity triggered by theta-burst stimulation (TBS). The schematic diagram of TBS application at synapses between layer 2/3 and corticogeniculate cells (CG) of layer 6 (A) and at synapses of white matter to CG cells in the visual cortex (B). C The graphs represent Hom-LTP of L2/3-evoked EPSPs (top) and het-LTD of WM-evoked EPSPs (bottom) triggered by TBS of the LII/III site. The means of EPSP slopes have been normalized to the control values 10–0 min before TBS for 14 cells as plotted against time. Circles and vertical bars indicate mean ± SEM. SEMs smaller than circles are not represented. The arrowheads below each plot exhibit the timing of TBS. D The graphs represent Hom-LTP of WM-evoked EPSPs initiated by TBS of the WM site and het-LTD of L2/3-evoked EPSPs (from Arami et al. [23])