Fig. 3

Mobility is maintained by co-administering FBX and uric acid in dys-1(tm4402); unc-22(e66) mutant animals. FBX (0, 5, 40 µg/ml), prednisone and uric acid (UA, 0, 2 mM) were added to dys-1(tm4402); unc-22(e66) mutant animals. twelve days after bleaching, nematode was placed on a new NGM plate with one animal each. After 30 min, the traces of worm movement were photographed. Representative images of worm tracking (A). The distance the worms traveled in 30 min was quantified (B). *P < 0.05, **** P < 0.0001. ns not significant