Fig. 1

FBX has a protective effect on body wall muscle cells in dys-1 mutant animals. A Wild-type and dys-1 mutant animals were cultured on a medium containing FBX at the concentration indicated on abscissae, and the numbers of body wall muscle cell nuclei in one bundle per animal were counted on Days 12. *P < 0.05, ***P = 0.0006, ****P < 0.0001. B Representative images of wild-type and dys-1 mutant animals’ mitochondria. Transgenic animals expressing mitoGFP in body wall muscle cells (ccIs4251 [Pmyo-3::mitoGFP]) were analyzed on Day 12 after bleach synchronization. C Representative images of wild-type and dys-1 mutant animals’ myofilament. Transgenic animals expressing GFP fusion MYO-3 protein in body wall muscle cells were analyzed on Day 12 after bleach synchronization. Right column Fig. are 2.7-fold magnification of the boxed area