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Table 2 Anthropometric characteristics and metabolic profile in the normal weight and obese subjects stratified by metabolic health

From: Relationship between the thrombospondin-1/Toll-like receptor 4 (TSP1/TLR4) pathway and vitamin D levels in obese and normal weight subjects with different metabolic phenotypes

 

Normal weight (n = 30)

Obese subject (n = 30)

F

p

MHNW (n = 16)

MUNW (n = 14)

MHO (n = 13)

MUO (n = 17)

BMI (kg/m2)

23.42 ± 0.25

24.28 ± 0.12

31.95ab ± 0.51

33.09ab ± 0.78

97.656*

< 0.001*

Waist circumference (cm)

95.56 ± 0.87

100.86 ± 1.45

113.62ab ± 2.34

120.76abc ± 2.41

39.599*

< 0.001*

Total cholesterol (mmol/L)

4.52 ± 0.05

5.22a ± 0.08

5.04a ± 0.04

5.98abc ± 0.15

39.838*

< 0.001*

Triglyceride (mmol/L)

1.48 ± 0.03

1.79a ± 0.03

1.67a ± 0.04

2.10abc ± 0.06

38.726*

< 0.001*

HDL-C (mmol/L)

1.10 ± 0.02

0.94a ± 0.01

1.02ab ± 0.01

0.93ac ± 0.01

52.264*

< 0.001*

LDL-C (mmol/L)

2.74 ± 0.05

3.46a ± 0.08

3.26a ± 0.03

4.09abc ± 0.13

46.470*

< 0.001*

FBG (mg/dL)

84.88 ± 2.62

93.29 ± 2.46

90.77 ± 2.18

90.59 ± 1.67

2.549

0.065

Insulin (µIU/mL)

5.28 ± 0.57

8.58 ± 0.71

8.63 ± 0.64

17.54abc ± 1.99

19.575*

< 0.001*

HOMA-IR

1.11 ± 0.13

2.02 ± 0.20

1.96 ± 0.16

3.99abc ± 0.49

17.014*

< 0.001*

hs-CRP (mg/L)

1.59 ± 0.18

2.23 ± 0.29

2.03 ± 0.22

5.32abc ± 0.63

19.122*

< 0.001*

  1. Data was expressed as mean ± standard error of mean (SEM). Post Hoc Test (Tukey) was used for pairwise comparison between each 2 groups
  2. MHNW metabolically healthy normal weight, MUNW metabolically unhealthy normal weight, MHO metabolically healthy obese, MUO metabolically unhealthy obese, F F for ANOVA test, p p value for comparing all the studied groups, BMI Body mass index, FBG fasting blood glucose, HDL-C high density lipoprotein cholesterol, hs-CRP high sensitivity C reactive protein, HOMA-IR homeostasis model assessment for insulin resistance, LDL-C low density lipoprotein cholesterol
  3. *Statistical significance at p < 0.05
  4. ap < 0.05 vs. MHNW
  5. bp < 0.05 vs. MUNW
  6. cp < 0.05 vs. MHO