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Table 1 Anthropometric and biochemical characteristics of the normal weight and obese subjects

From: Relationship between the thrombospondin-1/Toll-like receptor 4 (TSP1/TLR4) pathway and vitamin D levels in obese and normal weight subjects with different metabolic phenotypes

 

Normal weight (n = 30)

Obese (n = 30)

t

p

BMI (kg/m2)

23.82 ± 0.16

32.60 ± 0.50

16.752

< 0.001*

Waist circumference (cm)

98.03 ± 0.94

117.67 ± 1.80

9.668*

< 0.001*

Total cholesterol (mmol/L)

4.84 ± 0.08

5.58 ± 0.12

5.007*

< 0.001*

Triglyceride (mmol/L)

1.62 ± 0.04

1.92 ± 0.05

4.475*

< 0.001*

HDL-C (mmol/L)

1.02 ± 0.02

0.97 ± 0.01

2.717*

0.009*

LDL-C (mmol/L)

3.07 ± 0.08

3.73 ± 0.10

4.978*

< 0.001*

FBG (mg/dL)

88.80 ± 1.94

90.67 ± 1.32

0.796

0.430

Insulin (µIU/mL)

6.82 ± 0.54

13.68 ± 1.41

4.551*

< 0.001*

HOMA-IR

1.53 ± 0.14

3.11 ± 0.34

4.287*

< 0.001*

hs-CRP (mg/L)

1.89 ± 0.18

3.89 ± 0.47

3.969*

< 0.001*

25 (OH)D (ng/mL)

24.89 ± 1.15

10.67 ± 0.59

11.018*

< 0.001*

TSP1 (ng/mL)

10,394.03 ± 466.87

23,586.33 ± 494.15

19.406*

< 0.001*

TLR-4 (ng/mL)

0.71 ± 0.01

1.48 ± 0.06

11.966*

< 0.001*

TNF-α (pg/mL)

8.19 ± 0.15

12.06 ± 0.21

14.825*

< 0.001*

  1. Data was expressed by using mean ± standard error of mean (SEM)
  2. p p value for Student’s t-test for comparing between normal weight and obese subjects, t t value for Student’s t-test, BMI body mass index, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, FBG fasting blood glucose, HOMA-IR homeostasis model assessment for insulin resistance, hs-CRP high sensitivity C reactive protein, 25(OH)D 25 hydroxyvitamin D, TSP1 thrombospondin-1, TLR-4 Toll like receptor-4, TNF-α tumor necrosis factor-α
  3. *Statistical significance at p < 0.05