18 weeks of age | WT (n = 6) | Emd (n = 8) | H222P (n = 8) | EH (n = 8) |
---|---|---|---|---|
IVSd (mm) | 0.93 ± 0.10 | 0.99 ± 0.16 | 0.66 ± 0.11 ** | 0.71 ± 0.17 * |
LVIDd (mm) | 3.50 ± 0.27 | 3.50 ± 0.30 | 3.77 ± 0.34 | 4.05 ± 0.40 * |
LVPWd (mm) | 0.73 ± 0.09 | 0.84 ± 0.20 | 0.58 ± 0.09 | 0.64 ± 0.10 |
IVSs (mm) | 1.60 ± 0.14 | 1.73 ± 0.18 | 1.13 ± 0.12 *** | 1.25 ± 0.19 *** |
LVIDs (mm) | 1.75 ± 0.24 | 1.85 ± 0.24 | 2.50 ± 0.39 ** | 2.64 ± 0.60 ** |
LVPWs (mm) | 1.32 ± 0.12 | 1.34 ± 0.14 | 0.92 ± 0.13 *** | 1.07 ± 0.16 * |
EF (%) | 86.8 ± 3.1 | 85.1 ± 3.3 | 70.5 ± 6.2 *** | 72.0 ± 11.2 ** |
FS (%) | 49.8 ± 4.1 | 47.4 ± 4.2 | 33.9 ± 4.8 *** | 35.7 ± 7.9 *** |
HR (BPM) | 457 ± 17 | 483 ± 44 | 431 ± 31 | 458 ± 21 |
30 weeks of age | WT (n = 6) | Emd (n = 8) | H222P (n = 10) | EH (n = 12) |
---|---|---|---|---|
IVSd (mm) | 0.98 ± 0.08 | 1.08 ± 0.12 | 0.57 ± 0.16 *** | 0.76 ± 0.21 *, # |
LVIDd (mm) | 3.43 ± 0.14 | 3.68 ± 0.13 | 3.73 ± 0.27 | 3.73 ± 0.37 |
LVPWd (mm) | 0.95 ± 0.12 | 0.83 ± 0.17 | 0.65 ± 0.07 | 0.84 ± 0.42 |
IVSs (mm) | 1.78 ± 0.08 | 1.88 ± 0.15 | 1.10 ± 0.15 *** | 1.15 ± 0.25 *** |
LVIDs (mm) | 1.68 ± 0.16 | 1.68 ± 0.18 | 2.69 ± 0.30 *** | 2.79 ± 0.32 *** |
LVPWs (mm) | 1.63 ± 0.33 | 1.53 ± 0.17 | 0.92 ± 0.15 *** | 1.13 ± 0.36 ** |
EF (%) | 88.6 ± 2.6 | 90.2 ± 2.7 | 63.0 ± 5.8 *** | 58.1 ± 6.3 *** |
FS (%) | 51.7 ± 3.8 | 54.2 ± 4.2 | 28.4 ± 3.8 *** | 25.4 ± 3.9 *** |
HR (BPM) | 451 ± 55 | 448 ± 36 | 459 ± 52 | 445 ± 49 |