Fig. 1

Discovery of noradrenaline-storing cells in mouse tissues. A Noradrenaline-storing cells were observed from the dermis to hypodermis in the skin of mice. They were abundant in the epidermis and around hair follicles (arrows). Scale bars: 100 µm. Epi epidermis, Der dermis, dWAT dermal white adipose tissue, Pann. carn. panniculus carnosus, HF hair follicle, SG: sebaceous gland. B Noradrenaline-storing cells were observed in the periductal area (arrows) and in adipose tissues in mammary glands. Scale bar: 100 µm. Duct: mammary duct. C and D Noradrenaline-storing cells were abundant in the submucosa (arrows), and few were observed in the mucosa (arrowheads) in stomach (C) and small intestine (D). Scale bars: 200 µm in (C) and 100 µm in (D). E Noradrenaline-storing cells were abundant in the peribronchial area (arrows) of the lung but not in the alveoli. Scale bars: 100 µm. Bron: bronchus. F Noradrenaline-storing cells were found in the interstitium of the thymus but were not present in the parenchyma (arrows). Scale bar: 100 µm. G Noradrenaline-storing cells were absent in the islets and acini of the pancreas but present in the surrounding stroma (arrows). Scale bars: 100 or 50 µm. H–J Cells were not found in the liver (H), kidney (I), and heart (J). Scale bars: 50 µm. Glome. glomerulus. Three independent experiments were performed in each organ, and the representative pictures are shown in this Figure. Representative images of negative controls for primary antibody are shown in Additional file 1