Fig. 3

Typical example of the effect of WIN55,212-2 and time control on the slow ventral root potential (sVRP) in newborn rat spinal cord preparations. A Time course of changes in the peak amplitude of the sVRP in response to the application of 10 µM WIN55,212-2. B Examples of the reflex response in control (a), at 15 min after the administration of WIN55,212-2 (b), and after 15 min of washout (c). a–c correspond to a-c in panel A. C Data plots of the sVRP amplitude from 5 preparations at control (black), 15 min application of WIN55,212-2 (red), and 15 min after washout (blue). Bars on the right side of the individual datasets denote the mean ± S.D. The average values of the sVRP amplitude did not change significantly. D Time course of the changes in the peak amplitude of sVRP without drug application. E Examples of the reflex response. a-c correspond to a-c in panel A. F Data plots of the sVRP amplitude from 5 preparations at control (black), 30 min after control data acquisition (red), and 45 min after control data acquisition (blue). Bars on the right side of the individual datasets denote the mean ± S.D. The average values of the sVRP amplitude did not change significantly