Fig. 4
Time course of average normalized urine flow (nUF) (a), urinary glucose (Glu) concentration (b), urinary sodium concentration (c), urinary creatinine (Cr) concentration (d), urinary Glu excretion (e), urinary sodium excretion (f), and creatinine clearance (Ccr) per kidney (g). Data were obtained during the baseline (BL) period and after empagliflozin administration (T1, T2, and T3 periods). Data are mean ± standard error and individual rats (n = 9 post-myocardial infarction rats). The P values in the parentheses indicate the results of one-way repeated-measures analysis of variance. *P < 0.05, **P < 0.01, and ***P < 0.001, relative to BL by post hoc Dunnett’s test