Fig. 2

Blood glucose and plasma insulin levels after intragastric infusion of glucose in wild-type and T1R3-GFP-knockout mice. A Blood glucose levels before and 5, 10, 30, 60, and 90 min after intragastric infusion of glucose (2 mg/g body weight) in wild-type (WT) mice (n = 13) and T1R3-GFP-knockout (KO) mice (n = 9). B Plasma insulin levels before and 5, 10, 30, 60, and 90 min after intragastric infusion of glucose (2 mg/g body weight) in WT mice (n = 7) and T1R3-GFP-KO mice (n = 9). *P < 0.05, Student’s t-test with Bonferroni correction (WT vs. T1R3-GFP-KO). Data are presented as the mean ± standard error. C, D Plasma insulin levels at 0 and 5 min after intragastric infusion (IG) of glucose (2 mg/g body weight) in WT mice (C) and T1R3-GFP-KO mice (D). Box plots are as in Fig. 1E. Each point indicates individual data. NS no significant difference, paired t-test