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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Cumulative effects of exercise training and consumption of propolis on managing diabetic dyslipidemia in adult women: a single-blind, randomized, controlled trial with pre–post-intervention assessments

Fig. 2

Functional and molecular signaling pathway enrichment analysis. A The DAVID databases analysis suggested that most hub genes are involved in the etiology of type 2 diabetes mellitus. ADIPOQ initiates this pathogenic pathway. B–F Oxidative stress, detoxification of reactive oxygen species, cellular response to stress, heart ischemia, hypertension, diabetes, Wnt signaling pathway, apoptosis, and adipocytokine signaling pathway were also highlighted by the KOBAS-i, Wiki Pathway, Reactome, Elsevier pathway collection, and Panther databases. G, H Heart dysfunction and diabetes were identified as pathogenic processes associated with FAM132A, SFRP5, ADIPOQ, TNF, IL-6, C1QTNF1, CAT, SOD1, SOD2, and SOD3 by enrichment of hub genes in the DisGeNET and OMIM databases

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The Journal of Physiological Sciences

ISSN: 1880-6562

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