Fig. 5

The combination of FBX and sodium ascorbate prolongs the lifespan of wild-type (N2) animals. A–D Lifespan of N2 worms treated with different concentrations of FBX (0, 5, 10, and 20 µg/ml) and sodium ascorbate (Vit. C, 0 and 4 mM). A Log-rank P value: FBX 0 µg/ml vs FBX 0 µg/ml + Vit. C 4 mM = not significant. B Log-rank P value: FBX 0 µg/ml vs FBX 5 µg/ml = 0.0003. Log-rank P value: FBX 5 µg/ml vs FBX 5  µg /ml + Vit. C 4 mM = 0.1232. Log-rank P value: FBX 0 µg/ml vs FBX 5 µg/ml + Vit. C 4 mM < 0.0001. C Log-rank P value: FBX 0 µg/ml vs FBX 10 µg/ml = 0.0067. Log-rank P value: FBX 10 µg/ml vs FBX 10 µg/ml + Vit. C 4 mM = 0.052. Log-rank P value: FBX 0 µg/ml vs FBX 10 µg/ml + Vit. C 4 mM < 0.0001. D Log-rank P value: FBX 0 µg/ml vs FBX 20 µg/ml = 0.1442. Log-rank P value: FBX 20 µg/ml vs FBX 20 µg/ml + Vit. C 4 mM = 0.0129. Log-rank P value: FBX 0 µg/ml vs FBX 20 µg/ml + Vit. C 4 mM < 0.0001. Detailed P values are shown in Table 1. Median values, maximum lifespan, number of trials, and total number of animals are shown in Table 2