Fig. 2

Experimental protocols. In protocol 1 (n = 7), after baseline dialysate sampling (baseline 1), perfusate (Ringer's solution) was switched to 1 mM fluoxetine. The drug administration was continued for 60 min, then second baseline dialysate sampling was performed (baseline 2). The perfusate was then switched to 1 mM fluoxetine mixed with 1 mM pargyline. The drug administration was continued for 90 min. In protocol 2 (n = 7) and 3 (n = 7), similar experiments as protocol 1 were performed in the presence of 100 µM decynium-22 and the mixture of fluoxetine and decynium-22, respectively