Fig. 1
From: Transporter-dependent uptake and metabolism of myocardial interstitial serotonin in the rat heart
Schematic illustration of the microdialysis technique in the heart in vivo. A dialysis probe is implanted transversely into the lateral wall of the left ventricle. Myocardial interstitial 5-HT and 5-HIAA diffuses into perfusate across the dialysis membrane. Pharmacological agents diffuse into the interstitium according to a concentration gradient by reverse-microdialysis