Fig. 4

The increase in the firing rate of reticular neurons decreases cortical beta activity. The plot was derived from data of the same cell. The baseline condition is shown on the left and the tiagabine (200 nM) condition on the right. A Raster plots of activity of reticular cell before and during intrapallidal inhibition of GAT-1 by tiagabine. B Spectrograms showing the activity of reticular neurons (top) and motor cortex (bottom) at the beta frequency band. C Raw traces illustrating cortical activity in both basal and tiagabine conditions. Time scales apply to both traces