Fig. 2

Intrapallidal tiagabine increase reticular neurons’ (RTn) spiking rate without changes in their firing pattern. A Raw traces illustrating firing activity in both basal (left) and tiagabine (right) conditions; voltage and time scales apply to both traces. B Frequency histogram of the effect of intrapallidal tiagabine (200 nM) on RTn same cell as in A. C Heatmap of the spiking rate of individual reticular neurons before and posterior to pallidal infusion of both GAT-1 antagonists. D Statistics the effect of tiagabine applied in the ipsilateral globus pallidus on RTn neurons spiking rate (*P < 0.05 vs. control, paired Student´s t-test; n = 16 neurons). E. Statistics of burst index analysis, each symbol represents a neuron