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Table 2 Effect of tolfenamic acid on locomotor behaviour in malonic acid injected rats

From: Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats

Group

Exploration distance (mm)

Movement speed (mm/s)

Movement number

Non-exploration time (s)

Exploration time (s)

Sham

31933.13 ± 2173.29

66.53 ± 4.53

76.60 ± 4.53

73.94 ± 4.58

406.06 ± 4.58

MA

21916.30 ± 1425.99c

45.66 ± 2.97c

78.70 ± 4.71

103.39 ± 12.92b

376.61 ± 12.92b

TA 8 mg/kg

23956.65 ± 1532.72

49.91 ± 3.19

76.00 ± 2.94

119.65 ± 13.17

360.35 ± 13.17

TA 32 mg/kg

28304.47 ± 1578.96a

58.97 ± 3.29a

64.80 ± 4.46

77.16 ± 7.49

402.84 ± 7.49

  1. All of the results are expressed as the means ± SEM. n = 10
  2. ap < 0.05 vs. MA group
  3. bp < 0.05
  4. cp < 0.01 vs. sham group