Effects of continuous hypoxia on flow-mediated dilation in the cerebral and systemic circulation: on the regulatory significance of shear rate phenotype

Table 3 Cerebral flow-mediated dilation

Time	2 h			4 h		6 h		P values
Trial	Normoxia	Hypoxia		Normoxia	Hypoxia	Normoxia	Hypoxia	Time	Trial	Interaction
D_base (mm)	5.1 ± 0.7	5.3 ± 0.6	5.3 ± 0.7		5.4 ± 0.6	5.1 ± 0.6	5.2 ± 0.5	0.360	< 0.001	0.742
D_peak (mm)	5.3 ± 0.7	5.5 ± 0.7	5.5 ± 0.6		5.6 ± 0.6	5.3 ± 0.6	5.4 ± 0.6	0.451	< 0.001	0.724
ΔD (mm)	0.20 ± 0.13	0.20 ± 0.12	0.21 ± 0.06		0.20 ± 0.10	0.21 ± 0.12	0.23 ± 0.12	0.872	0.860	0.959
SR_AUC (a.u.)	47,490 ± 19,884	38,783 ± 15,567	45,474 ± 15,207		39,963 ± 14,721	41,379 ± 11,867	36,376 ± 10,821	0.413	0.059	0.972
Peak time (s)	148 ± 36	138 ± 27	148 ± 17		143 ± 25	141 ± 27	134 ± 37	0.784	0.454	0.983

Values are mean ± SD
D_base baseline diameter, D_peak peak diameter, ΔD the change in diameter from D_base to D_peak, SR_AUC shear rate area under the curve from the onset of hyperemia to peak dilation; Peak time, time to peak dilation from the onset of hyperemia
Bold p-values denote a p-value less than P<0.05. The Bold has now been removed

ISSN: 1880-6562