Effects of continuous hypoxia on flow-mediated dilation in the cerebral and systemic circulation: on the regulatory significance of shear rate phenotype

Table 2 Systemic flow-mediated dilation

Time	1 h		3 h			5 h		7 h		P values
Trial	Normoxia	Hypoxia	Normoxia		Hypoxia	Normoxia	Hypoxia	Normoxia	Hypoxia	Time	Trial	Interaction
D_base (mm)	4.1 ± 0.3	4.6 ± 1.1	4.5 ± 0.8	4.4 ± 0.3		4.3 ± 0.4	4.3 ± 0.2	4.3 ± 0.3	4.3 ± 0.2	0.852	0.343	0.164
D_peak (mm)	4.4 ± 0.3	4.9 ± 1.1	4.8 ± 0.8	4.7 ± 0.3		4.6 ± 0.3	4.6 ± 0.3	4.7 ± 0.3	4.6 ± 0.2	0.885	0.715	0.311
ΔD (mm)	0.32 ± 0.16	0.22 ± 0.12	0.29 ± 0.15	0.30 ± 0.13		0.35 ± 0.13	0.22 ± 0.11	0.34 ± 0.15	0.30 ± 0.12	0.032	0.667	0.323
SR_AUC (a.u.)	18,224 ± 8798	15,520 ± 6645	14,776 ± 7421	21,835 ± 6802		23,244 ± 5618	23,019 ± 7191	22,277 ± 5658	23,700 ± 7648	0.016	0.405	0.209
Peak time (s)	153 ± 14	151 ± 21	152 ± 26	177 ± 97		183 ± 43	143 ± 25	151 ± 15	164 ± 33	0.858	0.819	0.159

Values are mean ± SD
D_base baseline diameter, D_peak peak diameter, ΔD the change in diameter from D_base to D_peak, SR_AUC shear rate area under the curve from onset of hyperemia to peak dilation; Peak time, time to peak dilation from onset of hyperemia
Bold p-values denote a p-value less than P<0.05. The Bold has now been removed

ISSN: 1880-6562