Fig. 3

“Travel distance” and “Moving speed” on the Thermal Gradient Ring. A “Travel distance” in each temperature zone under the condition of 11.5–43.6 ℃ across a 60-min period (wild type n = 15, TRPA1^−/− n = 14, TRPM2^−/− n = 13, TRPAM8^−/− n = 14, TRPV1^−/− n = 11, TRPV3^−/− n = 13, TRPV4^−/− n = 15). B Transition of “Travel distance” as shown by whole temperature zones for each genotype in the first, middle, and last 20 min of the experiment. The color of each genotype is the same as shown in panel A. Mice were classified into two groups, as shown by the brackets. C “Moving speed” in each temperature zone under the condition of 11.5–43.6 ℃ in a 60-min period. The color of each genotype is the same as shown in panel A. Data from 11.5 ℃ to 17.3 ℃ and from 31.9 ℃ to 37.7 ℃ are enlarged. All error bars represent standard errors of the mean. Colors of asterisks and ns (not significant) indicate the comparison between wild-type mice and mice lacking TRP channels, as shown in panel A. * p < 0.05, ** p < 0.01 vs. wild type