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Fig. 4 | The Journal of Physiological Sciences

Fig. 4

From: Losartan treatment attenuates hindlimb unloading-induced atrophy in the soleus muscle of female rats via canonical TGF-β signaling

Fig. 4

Canonical TGF-β signaling transducer expression. Protein expression of GDF-8/myostatin (a and b) Smad2 (Ser465/467)/Smad3 (Ser423/425) phosphorylation ratio (c and d) on days 1 and 7 after unloading, and representative blots. CON, control; LOS, losartan. Samples were collected before (PRE), and on days 1 and 7 following hindlimb unloading. Values are expressed as mean ± standard deviation; n = 7 per time point. Normally distributed data were analyzed using two-way ANOVA. *P < 0.05 vs. PRE and P < 0.05 vs. CON of each sex

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