Fig. 2

CASC7 negatively regulated miR-34a-5p expression, whereas positively regulated TP73 expression. a qRT-PCR analysis of miR-34a-5p and TP73 expression in PTC tissues (n = 30) and adjacent normal tissues (n = 30). b Negative correlation between CASC7 expression and miR-34a-5p expression, and positive correlation between CASC7 expression and TP73 mRNA expression in PTC tissues (n = 30). c, f miR-34a-5p expression determined by qRT-PCR analysis, d, g TP73 mRNA expression determined by qRT-PCR analysis, and e, h TP73 protein level determined by western blot in human PTC cell lines (K1 and TPC-1) transfected with the CASC7 overexpression vector and empty vector. **P < 0.01 vs. Tumor-adjacent tissues or Vector. Data are expressed as the mean ± standard deviation (n = 3).