Fig. 2

A Arginine vasopressin (AVP)-enhanced green fluorescent protein (eGFP) and FosB-immunoreactivity (ir) in the paraventricular nucleus (PVN) 24 h after sham operation (A a–c) or bilateral adrenalectomy (ADX) (A d, e, f) in AVP-eGFP transgenic rats. Fluorescent microphotographs of the eGFP fluorescence and FosB-ir in the parvocellular division of the PVN are merged in A c, f. Scale bar = 100 µm. The scale bar of the inset in A f = 5 µm. B The eGFP fluorescence and FosB-ir in the PVN 12 h after i.p. administration of saline (B a–c) or cisplatin (B d–f) in AVP-eGFP transgenic rats. Fluorescent microphotographs of the eGFP fluorescence and FosB-ir in the parvocellular division of the PVN are merged in B c, f. Scale bar = 100 µm. The scale bar of the inset in A f = 5 µm. C The percentage of eGFP-expressing cells co-expressing FosB-ir in the parvocellular division of the PVN of AVP-eGFP transgenic rats 6, 12, and 24 h after i.p. administration of saline (B a–c) or cisplatin (B d–f) in AVP-eGFP transgenic rats. Data are presented as the mean ± SEM (for each group at each time point, n = 6). *P < 0.05, **P < 0.01 versus saline-treated group