Fig. 2

Effect of tolfenamic acid on the expression of p-tau and p-GSK-3β (Ser9) in hippocampus of P12 rats. Tolfenamic acid treatment (50 mg/kg, i.p.) for 4 and 6 h significantly decreased the expression of p-tau (Ser-202 and Ser-396) and increased the expression of p-GSK-3β (Ser9) and p-Akt (Ser473). All results are expressed as the mean ± SEM. n = 5; *p < 0.05, **p < 0.01 versus 0 h