Fig. 1
From: Effects of Hypericum scabrum extract on dentate gyrus synaptic plasticity in high fat diet-fed rats
Experimental timeline. Following 3Â months of high-fat diet (HFD) and administration of H. Scabrum extract in the experimental groups, with an intraperitoneal urethane rats were anesthetized and then put in a stereotaxic apparatus for surgery and electrophysiological recording. At least 20Â min of stable baseline response was taken and then, using a high-frequency stimulation protocol, long-term potentiation (LTP) was recorded