Fig. 2

Effects of 6-week donepezil on telemetry hemodynamics. a Weekly averaged heart rate (HR), b weekly averaged mean blood pressure (MBP) in CST and CDT rats. Each point represents the average of 1-week continuous data from all animals in each group (CST, n = 13; CDT, n = 14). HR decreased significantly from the 3rd week of the treatment in the CDT group, whereas MBP did not change. Values are means ± SEM. ^†P < 0.05, ^††P < 0.01 in CDT vs. CST; *P < 0.05, **P < 0.01 vs. pretreatment values (week 0) of each group by post hoc Dunnett’s test