Fig. 3From: Comparative study of hyperpolarization-activated currents in pulmonary vein cardiomyocytes isolated from rat, guinea pig, and rabbitIh in rat, guinea pig, and rabbit PV cardiomyocytes. Recordings from PV cardiomyocytes of rat (left), guinea pig (middle), and rabbit (right). Recordings in each animal were obtained in the same cell with 2-s hyperpolarizing pulses from − 40 mV to − 140 mV in 10 mV steps. Representative current traces were obtained in Tyrode solution containing 0.3 μM nisoldipine (top row). Then, the same pulse protocol was applied after addition of 1 mM Ba2+ (2nd row), 5 mM Cs+ (3rd row) and 1 mM Cd2+ (bottom row). The dashed line indicates 0 current levelBack to article page