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Fig. 1 | The Journal of Physiological Sciences

Fig. 1

From: Mechanism underlying the negative inotropic effect in rat left ventricle in hyperthermia: the role of TRPV1

Fig. 1

Effects of capsazepine (CPZ) in simultaneous recordings of blood pressure of a support rat; perfusion pressure (BP), left ventricular pressure (LVP), arteriovenous oxygen content difference (AVO2D), coronary blood flow (CBF), and circulatory blood temperature (Temp) at midrange left ventricular volume (mLVV) during heating at 42 °C in the absence (a) or presence of CPZ (b) in an excised, cross-circulated rat heart preparation. The open arrow in the left panel (a) indicates that the value of end-systolic pressure (ESP) on LVP gradually decreased from 146 to 110 mmHg until 42 °C after onset of heating, which was partially suppressed by the infusion of CPZ (approximately 1.23 µg/mL in blood) (b)

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