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Table 2 Responses to dietary medium-chain triglycerides for 5 days (N = 11)

From: A phase II, open-label clinical trial on the combination therapy with medium-chain triglycerides and ghrelin in patients with chronic obstructive pulmonary disease

 

Before (n = 11)

After (n = 11)

p value

Free fatty acids 8:0, μmoL/L

2.7 (1.4)

20.5 (10.4)

0.0010

Acyl ghrelin, fmoL/mL

8.6 (9.1)

20.0 (19.7)

0.0049

Des-acyl ghrelin, fmoL/mL

53.7 (44.3)

38.0 (27.8)

0.0098

Total ghrelin, fmoL/mL

62.3 (53.1)

57.9 (45.9)

0.3652

  1. Data are means (SD). Blood samples for the free fatty acids 8:0 in plasma were collected at 10:00 AM (2 h after the morning intake of 5 g of medium-chain triglycerides). Blood samples for acyl ghrelin and desacyl ghrelin were collected at 4:00 p.m. (4 h after the 12:00 p.m. intake of 5 g of medium-chain triglycerides, when the mean concentration of acyl ghrelin was the highest among the sampling periods. Change between before and after dietary MCT for 5 days by the Wilcoxon signed rank test