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Table 2 Responses to dietary medium-chain triglycerides for 5 days (N = 11)

From: A phase II, open-label clinical trial on the combination therapy with medium-chain triglycerides and ghrelin in patients with chronic obstructive pulmonary disease

 Before (n = 11)After (n = 11)p value
Free fatty acids 8:0, μmoL/L2.7 (1.4)20.5 (10.4)0.0010
Acyl ghrelin, fmoL/mL8.6 (9.1)20.0 (19.7)0.0049
Des-acyl ghrelin, fmoL/mL53.7 (44.3)38.0 (27.8)0.0098
Total ghrelin, fmoL/mL62.3 (53.1)57.9 (45.9)0.3652
  1. Data are means (SD). Blood samples for the free fatty acids 8:0 in plasma were collected at 10:00 AM (2 h after the morning intake of 5 g of medium-chain triglycerides). Blood samples for acyl ghrelin and desacyl ghrelin were collected at 4:00 p.m. (4 h after the 12:00 p.m. intake of 5 g of medium-chain triglycerides, when the mean concentration of acyl ghrelin was the highest among the sampling periods. Change between before and after dietary MCT for 5 days by the Wilcoxon signed rank test