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Fig. 2 | The Journal of Physiological Sciences

Fig. 2

From: Overexpression of calcitonin gene-related peptide protects mouse cerebral microvascular endothelial cells from high-glucose-induced damage via ERK/HIF-1/VEGF signaling

Fig. 2

Lenti-CGRP had no effect on cell viability but displayed an anti-apoptotic effect under high glucose conditions. a The results of the CCK-8 assay are expressed as OD values. b.END3 cells from different groups were treated with 25 mM glucose and 50 mM glucose for 1, 3, and 5 days. The data are shown as the mean ± SEM, *p < 0.05. b Representative flow cytometry images of cell apoptosis, as measured by the annexin V/PI method. Cells from different groups were treated with 25 mM or 50 mM glucose for 5 days. The graph shows the apoptosis rates of the different groups. The data are shown as the mean ± SEM, *p < 0.05

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