Fig. 4

Pyridoxine-induced neuropathy and investigation of the role and probable mechanism of CE in the rotarod test. a High dose of pyridoxine significantly decreased rotarod time compared to control (ctrl) group (*p < 0.001). b In the treatment group, CE increased rotarod time in comparison with saline group (NS) (*p < 0.001). MK-801 had no significant effect while picrotoxin (picro) decreased rotarod time compared to the CE group (#p < 0.001). Data are shown as mean ± SEM (N = 7 per group)