Fig. 4

The time-based changes of the Ca²⁺ transient “bump” characteristics during slow force response to sudden stretch. The changes in Ca²⁺ transient “bump” characteristics during the development of slow force response in normal (n = 6) and failing (n = 6) rat myocardium. a “Bump” amplitude. b “Bump” integral intensity. c “Bump” time-to-peak. All the characteristics are presented as a percentage of the first value after stretch. Scatter-plots of raw data (dots), median value (long thick lines) and 25–75% percentiles (short thin lines) are shown. The dotted line shows the level of “no change.” Asterisks indicate that the mean values are significantly different between CONT and MCT groups for the given time (Mann–Whitney U test, P < 0.05). NS no significant difference