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Table 2 Cardiac function and morphology parameters normalized to body weight

From: Cardiac basal autophagic activity and increased exercise capacity

  SC (n = 6) CMT (n = 6) HIIT (n = 6)
LV function parameters
 CO (ml min−1) 107 ± 18.0 79.1 ± 14.0a 72.2 ± 11.0a
 Cardiac index (ml min−1 kg−1) 0.167 ± 0.03 0.166 ± 0.04 0.152 ± 0.02
 LVEF (%) 74.8 ± 9.0 71.7 ± 3.8 71.7 ± 6.4
 HR (bpm) 332 ± 24 310 ± 31 286 ± 9.7b
 LVFS (%) 46.2 ± 8.4 42.6 ± 3.3 42.8 ± 5.6
 LVSV (μl) 323 ± 41 255 ± 32a 252 ± 35a
 LVSV index (ml beat kg−1) 0.50 ± 0.06 0.53 ± 0.09 0.53 ± 0.05
LV structural parameters
 LV mass/final BW (mg g−1) 1.51 ± 0.21 1.82 ± 0.18 1.88 ± 0.25a
 RWT (mm kg−1) 0.40 ± 0.05 0.42 ± 0.10 0.45 ± 0.07
 LVDD/final BW (mm kg−1) 13.8 ± 1.4 17.0 ± 1.9b 17.1 ± 1.1b
 LVSD/final BW (mm kg−1) 7.51 ± 1.8 9.73 ± 1.4 9.80 ± 1.5
 LVPWs/final BW (mm kg−1) 4.63 ± 0.51 6.24 ± 0.45b 6.20 ± 0.70b
 LVPWd/final BW (mm kg−1) 2.74 ± 0.15 3.53 ± 0.66b 3.78 ± 0.41b
 LVIDs/final BW (mm kg−1) 7.45 ± 1.4 9.66 ± 1.3 9.68 ± 1.5
 LVIDd/final BW (mm kg−1) 13.9 ± 1.4 16.9 ± 1.8b 17.0 ± 1.1b
 LVAWd/final BW (mm kg−1) 2.73 ± 0.34 3.53 ± 0.17b 3.53 ± 0.27b
 LVAWs/final BW (mm kg−1) 4.85 ± 0.43 6.11 ± 0.21b 0.61 ± 0.56b
 LVD vol (μl) 443 ± 98 356 ± 48 351 ± 61
 LVS vol (μl) 115 ± 65 99.4 ± 21 99.3 ± 40
  1. Values are reported as the mean ± standard deviation
  2. SC sedentary control, CMT continuous moderate–intensity training, HIIT high–intensity interval training, BW body weight, CO cardiac output, LVEF left ventricular ejection fraction, LVFS left ventricular fractional shortening, LVSV left ventricular stroke volume, cardiac index cardiac output/BW, LVSV index LV stroke volume/BW, HR heart rate, LV left ventricular, LVSD left ventricular end systolic diameters, LVDD left ventricular end diastolic diameters, LVAWd LV anterior wall thickness in diastole, LVAWs LV anterior wall thickness in systole, RWT relative wall thickness, LVIDd LV internal diameter in diastole, LVIDs LV internal diameter in systole, LVPWs LV posterior wall thickness in systole, LVD. vol LV end diastolic volume, LVS. vol LV end systolic volume
  3. ap < 0.05, b p < 0.01. Means with different superscripts in each row are significantly different from SC (one–way ANOVA followed by a Tukey’s post-hoc test)