Fig. 4From: Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium–coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12)Effect of PDZK1 on SMCT1 and SMCT2-mediated [3H]nicotinate transport activity. Coexpression of SMCT1 and PDZK1 increased [3H]nicotinate uptake (30 µM) significantly over cells transfected with SMCT1 alone (middle two columns) while coexpression of SMCT2 and PDZK1 did not increase [3H]nicotinate uptake (30 µM) over cells transfected with SMCT2 alone (right two columns). **p < 0.01Back to article page