Fig. 6
The stimulus–response functions (SRFs) of noxious-inhibitory units to graded pinching and to contact heat. a Raster plots of a MDm unit responded to applied forces (lower panel) by a hand-held pincher. b Averaged (mean ± SE) SRF of 21 noxious-inhibitory units showed the response significantly reduced at 455 gw. c Raster plots of the same MDm unit responded to 50 °C contact heat (lower panel). d Averaged SRF of 12 noxious-inhibitory units showed the response significantly reduced at 48 °C. *p < 0.05, compared to the baseline data (Kruskal–Wallis one-way ANOVA on ranks, post hoc analysis: Dunn’s test)