Table 1 The basal levels of the variables before and after administration of l-NAME or d-NAME in isolated perfused rat kidneys
Groups | l-NAME anaphylaxis (n = 6) | l-NAME control (n = 6) | d-NAME anaphylaxis (n = 6) | d-NAME control (n = 6) | ||||
|---|---|---|---|---|---|---|---|---|
Before | After | Before | After | Before | After | Before | After | |
Renal arterial blood pressure (mmHg) | 73 ± 2 | 70 ± 7 | 65 ± 4 | 62 ± 7 | 78 ± 2 | 83 ± 2 | 86 ± 3 | 88 ± 5 |
Renal venous pressure (mmHg) | 0.2 ± 0.1 | 0.1 ± 0.1 | 0.3 ± 0.1 | 0.2 ± 0.1 | 0.7 ± 0.1 | 0.8 ± 0.1 | 0.7 ± 0.2 | 0.8 ± 0.2 |
Mean renal arterial blood flow (ml/min/g) | 6.7 ± 0.3 | 3.9 ± 0.2*† | 7.4 ± 0.4 | 4.6 ± 0.7*† | 8.5 ± 0.3 | 8.5 ± 0.3 | 8.0 ± 0.3 | 8.0 ± 0.3 |
Renal vascular resistance (mmHg min/ml/g) | 11.1 ± 0.7 | 18.4 ± 2.2*† | 8.8 ± 0.6 | 15.7 ± 3.7* | 9.1 ± 0.4 | 9.8 ± 0.3 | 10.8 ± 0.9 | 11.1 ± 1.1 |