Fig. 3

The basal activity of the cerebellum increased in MD mice. a Schematic figure of caloric stimulation and data. Cold buffer was injected after recording the basal activity of the cerebellum for 300 s. b Graph showing the results of fast Fourier transform (FFT) prior (Pre) to the injection (upper panel) and a summary of all waves (lower panel). The basal activity of the cerebellum was higher in MD mice than in control mice. The graph shows the averages of 6 control and 7 MD mice. c Graph showing the results of FFT following (Post) the injection of the buffer (upper panel) and a summary of all waves (lower panel). Injection of cold water into the ear increased the activity of the cerebellum in both control and MD mice, but the activity was still higher in MD mice than in control mice. d Comparison between pre- (left) and post- (right) stimulation in both control and MD mice at 3–6 Hz. e An increase in power was particularly detected in the wave range of 3–6 Hz. In control mice, the power between 3.5 and 5.5 Hz significantly increased after caloric stimulation; in comparison, although an increase in power was also detected in MD mice, this increase was not statistically significant due to the higher basal activity of the cerebellum. Single asterisk indicates a significant difference at p < 0.05 by the paired t test, double asterisks indicate significant different at p < 0.01 by Student’s t test