Fig. 7

Impact of repeated intramuscular administration of 0.1, 1, and 5% DMSO on skeletal muscle regenerative capacity during the remodeling phase. a–c Quantitative analysis of EbMHC, myogenin, and vimentin protein expression, d F4/80⁺ infiltrated cells, and e regenerating muscle fiber CSA of no vehicle, 0.1, 1, and 5% DMSO administered groups. *p < 0.05, **p < 0.01, and ***p < 0.001 compared to no vehicle (n = 5 mice/group). f Histogram analysis of regenerating muscle fiber CSA between no vehicle vs. 5% DMSO administered group. The average number of measured regenerating muscle fiber CSA of no vehicle and 5% DMSO administered groups were 646 and 945 fibers/mice, respectively (n = 5 mice/group)