Fig. 5
From: Effects of voluntary exercise on antiretroviral therapy-induced neuropathic pain in mice
Voluntary wheel running reduced ddC treatment-induced increase in transient receptor potential cation channel subfamily V member 1 (TRPV1) expression in DRG nociceptive neurons. Top (a, b, c) Representative immunofluorescent images of DRG neurons expressing TRPV1 and DRG neuron markers. Bottom (a, b, c) Percentage of TRPV-1 based on anti-neurofilament 200- (NF200), anti-calcitonin gene-related peptide- (CGRP), and isothiocyanate-labeled isolectin B4- (IB4) positive nociceptive neurons in all counted DRG neurons. Significant difference at *P < 0.05 compared to saline and at # P < 0.05 compared to running/ddC group (n = 8/group)