Fig. 1

Number of completed repetitions (a), lactate (b), growth hormone (hGH; c), and insulin-like growth factor 1 (IGF-1; d) concentrations assessed prior to and after four sets of unilateral eccentric knee extensions that were performed until volitional muscle failure either with (open squares) or without (filled circles) blood flow restriction. Data are presented as means with 95% confidence intervals. Asterisks indicate significant difference (p < 0.05) from pre, pound keys indicate significant difference (p < 0.05) between groups. In cases where no significant group by time interactions were observed, asterisks above horizontal lines spanning adjacent bars indicate this measurement time point was significantly different (p < 0.05) from pre, collapsed across groups