Fig. 6
From: Xanthoceraside modulates neurogenesis to ameliorate cognitive impairment in APP/PS1 transgenic mice
Inhibition of the Wnt pathway affects xanthoceraside-mediated stimulatory effects on NSCs proliferation and neuronal differentiation in culture. a, c Representative immunofluorescent images showed that NSCs culture was treated with xanthoceraside in the presence and absence of the Wnt pathway inhibitor Dkk-1 in order to understand the effects on proliferation and differentiation. Scale bar = 20 μm. b, d Quantitative analysis of the proliferation and differentiation of NSCs. Scale bar = 50 μm. Values are expressed as the mean ± SEM (n = 3). ### p < 0.001 vs. control; *p < 0.05 and **p < 0.01 vs. Aβ25–35; $$ p < 0.01 and $$$ p < 0.001 vs. Aβ25–35 + xanthoceraside