Fig. 4

Metabolic parameters of control (CTL), obese (DIO) and trained obese (DIO-EXE) groups. a Insulin tolerance test curve. b Rate constant of plasma glucose disappearance (KITT) in the insulin tolerance test curve. c Serum free fatty acids after 6 h of fasting. d Fasting glucose after 6 h of fasting collected from tail blood. e Fasting Insulin after 6 h of fasting measured in plasma. Bars represent means and SEM of CTL, DIO and DIO-EXE mice (n = 7–10). *p < 0.05 for CTL versus DIO group; ^# p < 0.05 for CTL versus DIO-EXE group; ^$ p < 0.05 for DIO versus DIO-EXE group