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Table 2 Binding characteristics of β-ARs

From: β-Adrenergic signaling, monoamine oxidase A and antioxidant defence in the myocardium of SHR and SHR-mtBN conplastic rat strains: the effect of chronic hypoxia

  SHR SHR/H SHR-mtBN SHR-mtBN/H
B max (fmol mg−1) 21.71 ± 0.88 25.20 ± 0.38+ 24.87 ± 0.73 18.37 ± 0.46§#
K D (nM) 0.49 ± 0.10 0.58 ± 0.07 0.51 ± 0.03 0.32 ± 0.01
  1. Data are means (±SEM) of three separate experiments performed in triplicates
  2. B max maximal binding capacity, K D equilibrium dissociation constant of radioligand ([3H]CGP 12177)
  3. + p < 0.05 SHR vs. SHR/H; § p < 0.05 SHR/H vs. SHR-mtBN/H rats; # p < 0.05 SHR-mtBN vs. SHR-mtBN/H