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Table 2 Contribution of ENDO/EPI differences in individual ionic currents to differences in action potential, Ca2+ transient, and contraction between the ENDO/EPI cellular models

From: Transmural cellular heterogeneity in myocardial electromechanics

Ionic current

RP

APD10

APD50

APD90

CaT70

CaT90

T max

TR75

i pNa

0.99

1.08

1.08

1.08

1.00

0.97

1.08

1.13

i Kr

0.99

1.06

1.06

1.06

1.00

0.97

1.07

1.13

i Ks

0.99

1.21

1.18

1.17

1.00

0.97

1.09

1.19

i CaL

0.99

1.35

1.13

1.11

1.00

0.97

1.13

1.22

i bCa

1.00

1.05

1.05

1.05

1.00

0.97

1.08

1.13

i NaK / i NaCa

0.99

1.20

1.11

1.10

1.00

0.97

1.03

1.08

Total

0.99

1.31

1.26

1.25

1.00

0.97

1.06

1.14

  1. The ENDO/EPI ratio between the characteristics produced by the models at isometric twitches is shown
  2. RP resting membrane potential; APD 10,50,90 action potential duration at 10, 50 and 90% repolarization, respectively; CaT 70,90 calcium transient duration at 70 and 90% decay, respectively; T max time to peak contraction; TR 75 time to 75% relaxation (measured as the time interval from T max to the time of 75% relaxation)
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The Journal of Physiological Sciences

ISSN: 1880-6562

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